ABSTRACT
A facile regio and stereoselective synthesis of novel spiro[indolin-3,2′-pyrrolidin]-2-one’s have been accomplished through 1,3-dipolar cycloaddition of azomethine ylides generated in situ from the reaction of isatin and benzyl amine with quinoline bearing dipolarophiles in good yields. The synthesized compounds were well characterized through different spectroscopic techniques, such as single crystal XRD, FTIR, NMR, and mass spectral analysis.
GRAPHICAL ABSTRACT
Acknowledgment
The authors thank SAIF, Cochin University of Science and Technology, Cochin and SAIF, Punjab University for taking NMR and mass spectral analysis.