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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 11
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Original Articles

Montmorillonite K10-catalyzed synthesis of N-fused imino-1,2,4-thiadiazolo isoquinoline derivatives

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Pages 1363-1376 | Received 08 Dec 2017, Published online: 02 Apr 2018
 

ABSTRACT

A novel synthesis of N-fused imino-1,2,4-thiadiazolo derivatives is described. This approach involves the inexpensive, nontoxic, recoverable, and easy to handle montmorillonite K10 that catalyzes the coupling of 3-aminoisoquinolines and phenylisothiocyanates to afford the N-fused imino-1,2,4-thiadiazolo isoquinoline motifs in exemplary yields. The main attractions of this synthetic strategy were simple procedure and excellent yields.

GRAPHICAL ABSTRACT

Additional information

Funding

The authors acknowledge the financial support from the Department of Science and Technology - Science and Engineering Research Board (DST-SERB), India, under Fast Track Young Scientist Scheme in the form of major research project (No. SB/FT/CS-028/2013 dated: 09.06.2014, 24.09.2015 and 12.09.2016).

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