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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 14
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Synthetic Communications Review

Zinc-catalyzed multicomponent reactions: Facile synthesis of fully substituted pyridines

, &
Pages 1777-1785 | Received 07 Feb 2018, Published online: 29 May 2018
 

Abstract

A first example of environmentally benign zinc complex catalyzed one-pot four-component reaction between malononitrile, ketone, ammonium acetate and aromatic aldehyde for the facile synthesis of fully substituted pyridines just within 2 min in environmentally friendly solvent ethanol has been optimized.

GRAPHICAL ABSTRACT

Acknowledgements

RK thanks the MHRD, New Delhi for a research fellowship.

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