Highly efficient reduction of nitro compounds: Recyclable Pd/C-catalyzed transfer hydrogenation with ammonium formate or hydrazine hydrate as hydrogen source

Abstract

Herein, we described a highly efficient heterogeneous Pd/C-catalyzed transfer hydrogenation of nitro compounds for the synthesis of primary amines, using ammonium formate and hydrazine hydrate as hydrogen source independently. The products were obtained with up to >99% yield. Furthermore, gram scale and recycling of catalyst had been tested with well results.

Graphical Abstract

Keywords:

• Ammonium formate
• hydrazine hydrate
• nitro compounds
• palladium
• transfer hydrogenation

Additional information

Funding

The work was supported by the Youth Science and Technology Talent Development Project in Education Department of Guizhou Province [grant number qianjiaohe KY zi [2017] number 261], the Union Foundation of Science and Technology Department of Guizhou Province [grant number qiankehe LH zi [2015] number 7614], and Innovation Team of Liupanshui Normal University [grant number LPSSYKJTD201601].