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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 19
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Articles

MgSiO3 NPs catalyzed intramolecular cycloaddition reaction: A simple and stereoselective synthesis of unprecedented julolidine analogs

, , , , , & show all
Pages 2485-2495 | Received 12 Apr 2018, Published online: 10 Oct 2018
 

Abstract

A new julolidine hybrid analogs have been accomplished in a regio and stereo controlled manner using heterogenous MgSiO3 nanoparticles (NPs) catalyzed intramolecular dipolar cycloaddition reaction as a key step. The synthesized catalyst was used in the preparation of various new julolidine analogs with a good yield ranging from 65 to 85%. Further, catalyst could be recycled in several times without loss of significant activity which was an added advantage to the principles of green chemistry.

GRAPHICAL ABSTRACT

Disclosure statement

No potential conflict of interest was reported by the authors.

Supporting information

Experimental data and characterization of all new compounds.

Additional information

Funding

The authors express their gratitude to RFTT scheme of VGST, Govt of Karnataka and Fast-Track scheme of DST-SERB for financial support. This work was also supported by Department of Science and Technology, Ministry of Science and Technology.

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