Synthesis of substituted ureas possessing alkyl aromatic fragments via the reaction of 1-(3,3-diethoxypropyl)ureas with phenols

Andrey V. SmolobochkinArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Kazan, Russian FederationCorrespondence[email protected]
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Almir S. GazizovArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Kazan, Russian FederationView further author information

Alexander R. BurilovArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Kazan, Russian FederationView further author information

Michail A. PudovikArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Kazan, Russian FederationView further author information

Abstract

In this article, we report the approach to the substituted ureas based on the reaction of 1-(3,3-diethoxypropyl)ureas with phenols. Depending on the nature of the phenol and urea the reaction leads either to diarylpropane and dibenzoxanthene derivatives or calixarenes. The proposed method benefits from mild reaction conditions, high product yields and operational simplicity.

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Funding

The reported study was funded by RFBR according to the research project № 18-33-00206.

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Synthesis of substituted ureas possessing alkyl aromatic fragments via the reaction of 1-(3,3-diethoxypropyl)ureas with phenols

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Synthesis of substituted ureas possessing alkyl aromatic fragments via the reaction of 1-(3,3-diethoxypropyl)ureas with phenols

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