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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 19
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Articles

A microwave-promoted atom-efficient diesterification of aromatic carboxylate with 1,4-dibromobutane in water

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Pages 2559-2565 | Received 26 Mar 2018, Published online: 12 Oct 2018
 

Abstract

A rapid and efficient diesterification reaction of aromatic carboxylate with 1,4-dibromobutane was carried out in water at 100 °C in the presence of base and phase transfer catalyst under focused microwave irradiation. This microwave-promoted protocol offers an atom-efficient and environment-friendly approach to synthesize butamethylenediesters in high yield.

Graphical Abstract

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