FeCl₃ catalyzed prins cylization for the synthesis of angularly fused polycyclic scaffolds

Abstract

A catalytic amount of FeCl₃ is found to be effective for the synthesis of fused furo[3,2-c]pyrano[2,3-b]chromene derivatives through a tandem Prins type cyclization. The reaction proceeds smoothly in the presence of 10 mol% FeCl₃ in dichloromethane at room temperature and the corresponding products are isolated in good yields.

Graphical Abstract

Keywords:

• Alcohol tethered enol ethers
• aldehydes
• fused heterocycles
• iron catalysis
• tandem process

Additional information

Funding

This work was supported by K L University.