Abstract
A simple, efficient, and metal-free methodology for the preparation of 2-mercaptobenzothiazole and derivatives in excellent yields via microwave-assisted pathway is reported. Our condition provides a convenient protocol for the synthesis of a diverse collection of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles with a very simple purification process. This report provides an alternative protocol for fast access to the wide range of compounds for sequence synthesis and biological studies.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the author(s).
Supporting Information
Full experimental detail, characterization data of new compounds, 1H and 13C NMR spectra. This material can be found via the “Supplementary Content” section of this article’s webpage.