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This study describes the synthesis of novel polycyclic spiropyrrolidine oxindoles through the 1,3-dipolar cycloaddition of azomethine ylides generated in situ with 3-(arylmethylene)-indolin-2-ones. Effect of substituents of azomethine ylides and various dipolarophiles on reactivity, as well as on the products regio- and stereoselectivity was investigated.
The authors acknowledge Barbara Balázs and Tamás Gáti for spectral measurements.
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