Gram scale synthesis of alpha-cyanoalkylboronic esters via direct B–B and C–N bond cleavage

Abstract

A direct metal-free approach for the synthesis of alpha-cyanoalkylboronic esters from bis-diboron ester and azobis-nitrile compound is reported under ambient temperature and pressure via a free radical procedure.

Graphical Abstract

Keywords:

• Azobis-nitrile
• bis-diboron ester
• metal-free
• radical

Additional information

Funding

We sincerely acknowledge the Department of Science and Tech-nology (DST), Government of India [Grant No. EEQ/2016/000518], INSPIRE-DST, Government of India [Grant 04/2013/000751] and NIT Rourkela.