Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 50, 2020 - Issue 22
995
Views
28
CrossRef citations to date
0
Altmetric
SYNTHETIC COMMUNICATIONS REVIEWS

Transition metal catalyzed Glaser and Glaser-Hay coupling reactions: Scope, classical/green methodologies and synthetic applications

& ORCID Icon
Pages 3337-3368 | Received 16 May 2020, Published online: 08 Aug 2020
 

Abstract

Glaser coupling is one of the most important modern organic tool for the formation of carbon-carbon triple bond and has also been extensively used for the synthesis of polymers, macrocycles and oligomers (known for their electrochemical, optical and electronic properties). Although this reaction is generally catalyzed by copper complexes yet recent advances including new ligands, additives and silver/cobalt/palladium catalysts make this coupling reaction more effective. This review highlights the role of various catalytic systems used in Glaser- and Glaser-Hay coupling reactions for the production of a variety of C-C triple bonds with wide structural features.

Graphical Abstract

Acknowledgments

The authors are thankful to GC University, Faisalabad, for providing the facilities to carry out this work.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.