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Abstract
An efficient total synthesis of Berkeleylactone F has been synthesized from the known starting materials. The key steps involved in the synthesis are Wittig reaction, epoxide ring opening with 1, 3-dithiane and Yamaguchi macrolactonization.
Graphical Abstract
Acknowledgments
The authors are thankful to Department of Chemistry, Koneru Lakshmaiah Education Foundation, Guntur and GVK Biosciences, Pvt. Ltd for providing facilities to carry out our research work.
Additional information
Funding
The authors are grateful to the Deanship of Scientific Research, King Khalid University for the financial support [Grant No. RGP. 1/185/42].