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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 52, 2022 - Issue 15
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Articles

Microwave-assisted synthesis and reactivity of new 5-amino-1H-pyrazole derivatives bearing 2-furoyl moieties

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Pages 1590-1601 | Received 25 Apr 2022, Published online: 14 Jul 2022
 

Abstract

In this study, a novel series of 5-amino-1H-pyrazole derivatives involving 2-furoyl moieties were synthesized in good yields from 2-cyano-3 ethoxyacrylonitrile or ethyl-2-cyano-3-ethoxyacrylate and of various furan-2-carbohydrazide compounds under microwave irradiation. We studied the reactivity of these new compounds toward the orthoesters using the same methodology. All structures were confirmed by analytical and spectral (FT-IR, 1H NMR, 13C NMR, and elemental analysis) techniques.

Graphical Abstract

Acknowledgements

The authors acknowledge the “Ministry of Higher Education, Scientific Research and Technology, Tunisia,” for the support of this study.

Disclosure statement

The authors declare that they have no competing interests and non-financial competing interests.

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