A short review on the synthesis of pyrrolo[3,4-c]coumarins an isolamellarin-B scaffolds

Abstract

This review presents a vast body of literature on various synthetic methodology, biological, and fluorescence activities of pyrrolo[3,4‑c]coumarins as published during the last 20–30 years. Synthesized pyrrolo[3,4‑c]coumarins have been reported in the literature by the construction of either pyrrole, indole, or both rings via different synthetic methodology including metal-catalyzed reactions, and green reaction protocols starting from readily accessible substrates.

Graphical Abstract

This review presents the different synthetic approach of pyrrolo[3,4‑c]coumarins an isolamellarin-B via classical, metal-catalyzed and green reaction protocols starting from suitable precursors.

Keywords:

• 1,3-dipolar-cycloaddition
• condensation-cyclization
• isolamellarin-B
• lamellarin
• pyrrolo[3,4‑c]coumarins

Acknowledgments

We thank Professor Gandhi Kumar Kar, Partha Pratim Mukhopadhyay and Dr. Pradipta Ghosh for their valuable suggestions.

Additional information

Funding

We sincerely thank the Department of Higher Education, Science & Technology and Biotechnology, West Bengal, for financial help [368 (Sanc.)/STBT-11012(25)/11/2020-ST SEC Date 14/07/2021]