One-Pot Synthesis of 2-Amino-5,10-dihydro-5,10-dioxo-4-phenyl-4H-benzo[g]chromene Derivatives Catalyzed by ZnCl₂

Abstract

An efficient one-pot synthesis of 2-amino-5,10-dihydro-5,10-dioxo-4-phenyl-4H-benzo[g]chromene derivatives has been achieved by the reaction of 2-hydroxynaphthalene-1,4-dione, cyanothioacetamide, and aromaticaldehyde in EtOH at room temperature catalyzed by ZnCl₂. The structures of the products were characterized by infrared, ¹H NMR, mass, and elemental analysis.

Keywords:

• Benzo[g]chromene
• cyanothioacetamide
• lawsone
• one-pot synthesis
• ZnCl₂

ACKNOWLEDGMENT

We thank the University Grants Commission, New Delhi (F. No. 32-201/2006 (SR)), for financial support.