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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 5
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Original Articles

Synthesis of 2-Arylbenzimidazoles in Water

Siva S. Panda Department of Chemistry, University of Delhi, Delhi, India
&
Subhash C. Jain Department of Chemistry, University of Delhi, Delhi, IndiaCorrespondence[email protected]
Pages 729-735 | Received 06 Oct 2009, Published online: 31 Jan 2011
 
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Abstract

A simple and efficient procedure for the synthesis of 2-arylbenzimidazoles through a one-pot condensation of o-phenylenediamines with aryl aldehydes in water is described. Short reaction time, large-scale synthesis, easy and quick isolation of the product, and excellent yield are the main advantages of this procedure.

ACKNOWLEDGMENT

The authors gratefully acknowledge financial support from the University Grant Commission, New Delhi.

Notes

a Isolated product.

b Resulting 2-arylbenzimidazole.

a Reaction time 2 h.

b Isolated product.

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