Acylation of Aromatic Ethers Using Different Carboxylic Acid Anhydrides as Acylating Agents in the Presence of Nontoxic, Noncorrosive Resin Amberlyst 15 as a Solid Acid Catalyst

Abstract

Friedel–Crafts acylation of aromatic ethers, anisole, 2-methoxynaphthalene, and dimethoxybenzenes with different acid anhydrides is carried out in the presence of an inexpensive and nonhazardous solid acid, Amberlyst 15. The catalyst is reusable, thus making the process environmentally friendly.

Keywords:

• Acid anhydrides
• acylation
• Amberlyst 15
• Friedel–Crafts reaction

ACKNOWLEDGMENT

Financial support by the government of India under the “Technical Education Quality Improvement Programme” (TEQIP) is gratefully acknowledged.

Notes

Note. Reaction conditions: Veratrole (10 mmol), acetic anhydride (10 mmol), 80 °C, solvent EDC (10 mL), time 10 h.

^a Wt% with regard to amount of veratrole.

^b GC analysis.

Note. Reaction conditions: Aromatic ether (10 mmol), acid anhydride (10 mmol), catalyst: Amberlyst 15, 20 wt% with regard to weight of aromatic ether, 80 °C, solvent EDC (10 mL), time 10 h.

^a GC and GC-MS analysis.