Abstract
The synthesis of benzimidazoles has been achieved in a one-pot reaction in excellent yield using a newly developed methodology. 2,5-Disubstituted-3-cyanoacetyl indoles were directly condensed with substituted orthophenylenediamine via microwave irradiation under neat, solid support, and conventional conditions in a short time to afford the corresponding products in good yields. Structures of the products thus obtained were confirmed by their melting points, infrared, 1H NMR, 13C NMR, and mass spectral data.
ACKNOWLEDGMENTS
The authors thank the chairman, Department of Chemistry, Gulbarga University, Gulbarga, for providing laboratory facilities and Punjab University Chandigarh, Central University Hyderabad, Indian Institute for Chemical Technology, Hyderabad, for spectral and analytical data.