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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 7
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Original Articles

Improved Synthesis of Monoprotected 5- and 6-Amino-2-azanorbornanes

, , , , , & show all
Pages 981-992 | Received 01 Dec 2009, Published online: 03 Mar 2011
 

Abstract

An improved synthesis of Boc-monoprotected 5- and 6-amino-2-azanorbornanes is reported. The synthetic scheme consists of five steps and allows multigram quantities of the title compounds to be obtained. The regio- and stereochemistries of the products are established by two-dimensional NMR experiments.

ACKNOWLEDGMENT

The authors are thankful to Mr. Vitaliy Polovinko for the 2D NMR experiments.

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