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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 2, 1972 - Issue 1
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Original Articles

Direct Esterification of Carboxylic Acid with Alkyl Halide by Cu(I) Oxide

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Pages 1-6 | Received 25 Oct 1971, Published online: 03 Jan 2007
 

Abstract

Esterification is one of the most fundamental synthetic reaactions, for which many methods have been known.1) The present communication describes a new method of esterification of carboxylic acid with alkyl halide using Cu2o-base system. As the base component, isonitrile and pypridine are suitable. This new method was found in the course of the studies upon the exploration of the catalysis of Cu(I)-isonitrilecomplex.

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