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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 2, 1972 - Issue 2
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Original Articles

An α-Lactam as an Alkilating Agent

István Langyel Department of Chemistry, St. Jone's University, Jamaica, New York, 11432
&
Robert V. Mark Department of Chemistry, St. Jone's University, Jamaica, New York, 11432
Pages 109-112 | Received 03 Nov 1971, Published online: 26 Jan 2007
 
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Abstract

The ‘normal’ reaction of α-lactams (aziridinones) is mcleophilic ring ening,1 which can occur with fission of either one of the three bonds (a-b-c), depending on the reagent, to yield and acyclic addition prodnct (I,II,III).2

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