Abstract
We wish to report the synthesis of L-α-amino-γ-nitroguanidinobutyric acid, a hitherto unkonwn amino acid derivative. This derivative can be the base for preparing peptides (for instance hormonse) contairing Lα-amono-γ-guanidinobutyric acid, the lower homologue of L-arginine. The higher homologue, L-homoarginine, has already been built in peptides through its nitroderivative, as was the case with angiotensin IIanalogues1and Har-Bradykinin2.