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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 3, 1973 - Issue 2
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Original Articles

Dequaternization of Ammonium Salts by Nucleophiles

Pages 99-100 | Received 16 Jan 1973, Published online: 06 Dec 2006
 

Abstract

Recently we have demonstrated the dealkylation of quaternary ammonium compounds by 1,4-diazabicyclo[2,2,2]octane.1 It is believed that an alkyl exchange is involved in this reaction. With the objective of further developing new dequaternization methods, a number of nucleophiles has since been examined for their effectiveness. This communication discloses our results of this investigation.

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