The Synthesis of Some 9-,10-, and 11-Membered Ring Compounds Containing a Nitrogen Atom: 2,3,4,5,6,7-Hexahydro-1H-3-Benzazonines, 1,2,3,4,5,6,7,8-Octahydro-3-Benzazocines, and 2,3,4,5,6,7,8,9-Octahydro-1H-3-Benzazacy-cloundecanes

Abstract

In previous papers the syntheses of seven-¹ and eight-membered ^{2a, 2b} ring compounds of the general formulas 5a, b have been described and the nine-membered^2c homolog^5c briefly mentioned. It was of interest to see whether the method of ring formation using an amino acid of type 3 was applicable to the preparation of larger ring systems. In this paper we would like to report the preparation of the bicyclic amines 5 which are the 9-, 10-, and 11-membered ring homologs of this series.