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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 5, 1975 - Issue 4
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Original Articles

Cleavage of Methyl and Benzyl Esters by Thiocyanate

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Pages 305-307 | Received 21 Mar 1975, Published online: 05 Dec 2006
 

Abstract

Growing attention is being accorded to nonsaponific cleavage of esters. Strong nucleophiles (LiI,1 RS, 2) have been exploited successfully to effect rupture of 0-alkyl bonds in methyl and a few other esters. As reagents of this sort are still quite limited, we felt that it may be of interest to provide some alternatives.

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