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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 6, 1976 - Issue 5
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Original Articles

New Synthetic Pathways to Tilorone Hydrochloride

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Pages 371-376 | Received 23 Mar 1976, Published online: 06 Dec 2006
 

Abstract

Tilorone hydrochloride (1), the dihydrochloride of

bis-2, 7-[(diethylamino)ethoxy]fluoren-9-one, is an orally active, interferon stimulating, antiviral agent in mice.1,2 Extensive studies have also shown the effectiveness of this compound as an antitumor and antiinflammatory agent.3,4 Tilorone hydrochloride is currently being investigated as an adjuvant in the early treatment of cancer.5

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