Carboxychloro Olefination: A Convenient Synthesis of α-Chloro α, β-Ethylenic Carboxylic Acids

Abstract

Diethylchloromethylphosphonate has received little attention considering the possible application for this type of reagent. Recently we have introduced the use of the organolithium reagent of this phosphorus derivative for the conversion of carbonyl compounds into dichloro or dibromo olefins and epoxyphosphonates¹.