The Synthesis of 6-Hydroxy-2H-pyran-3(6H)-onyl-hexoses, Potential Precursors of Disaccharides

Abstract

6-Hydroxy-2H-pyran-3(6H) -one (1)¹, a highly functionalized synthone, was recently employed for the synthesis of pyromeconic acid², phosphorus containing sugars³, and for the synthesis of all stereoisomeric pentoses⁴. Formation of a glycosidic linkage between 1 and monosaccharides would open an access to a variety of disaccharides via the proper modification of the 3-pyrone moiety.