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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 9, 1979 - Issue 6
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Original Articles

A Mild Method for the Esterification of Fatty Acids

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Pages 539-543 | Received 22 Jan 1979, Published online: 05 Dec 2006
 

Abstract

In conjunction with a synthetic problem, we were in need of a method for the stoichiometric esterification of fatty acids, containing the aqueous acid labile tert-butyl dimethylsilyloxy group (OTBS), with a variety of alcohols. It has been reported2 that fatty acids form acylureas in the presence of dicyclo-hexylcarbodiimide (DCC) and methanol3 without esterification.

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