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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 9, 1979 - Issue 10
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Original Articles

Synthesis of Unsymmetrically Substituted Hexahydroimidazo [4,5-d] Imidazole-2,5-diones and Elucidation of Reaction Pathways

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Pages 863-870 | Received 21 May 1979, Published online: 06 Dec 2006
 

Abstract

We have reported the synthesis and structural elucidation of a series of hexahydroimidazo [4,5-d] imidazole-2,5-diones and hydantoins from glyoxal and substituted ureas.1,2 The general equation of this condensation reaction and a few representative compounds: those reported, current and hypothetical, are depicted in Scheme 1.

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