Novel Synthesis of 4,5-Trisubstituted Dioxolanes via Methylthiomethyl Ethers

Abstract

The protection of a variety of primary,¹ secondary² and tertiary^2,3 alcohols and phenols⁴ as methylthiomethyl (MTM) ethers has recently been described. During the course of studies in our laboratory, we observed the novel formation of dioxolanes upon deprotection of α-hydroxy tertiary MTM ethers and we report our results in this communication.