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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 12, 1982 - Issue 13
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Original Articles

An Alternative Procedure for the Aluminum-Mediated Conversion of Esters to Amides

Jeremy I. Levin Department of Chemistry, The Pennsylvania State University, University Park, PA, 16802
,
Edward Turos Department of Chemistry, The Pennsylvania State University, University Park, PA, 16802
&
Steven M. Weinreb Department of Chemistry, The Pennsylvania State University, University Park, PA, 16802
Pages 989-993 | Published online: 06 Dec 2006
 
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Abstract

A convenient method has been developed for directly converting esters to amides using reagents derived from the reaction of trimethylaluminum with ammonium chloride, methylamine hydrochloride or dimethylamine hydrochloride.

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