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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 12, 1982 - Issue 6
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Original Articles

Sodium Borohydride-t-butyl Alcohol-Methanol as an Efficient System for the Selective Reduction of Esters

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Pages 463-467 | Published online: 05 Dec 2006
 

Abstract

Reduction of esters to the corresponding primary alcohols by metal hydrides is an important synthetic reaction.1 One may often encounter the problem of the selective reduction of esters in the presence of other functional groups such as amide, carboxylic acid or nitrile.2

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