Abstract
Substituted oxazoles were recognized as intermediates for the synthesis of antibiotics1 and used as azadienes in Diel's-Alder reactions.2-5 Certain oxazole derivatives have been reported to possess biological activities such as hypertensive,6 analgesic,7 fungicide,8 antiinflammatory9', 10antiviral,11 antibacterial,11 antitubercular12 and anticonvulsant.13 These synthetic and pharmaceutical significance prompted us to undertake the synthesis of steroidal oxazoles (2-a and 2-b) from easily accessible steroidal oximes (1-a and 1-b).