Abstract
The conformational analysis of six-membered ring compounds such as mono- and disubstituted cyclohexane is a well-documented subject, and hence prediction of the most stable conformation of a given compound can be in general achieved with reasonable accuracy either by use of thermodynamic data or by spectroscopic methods.1) When considering polysubstituted cyclohexane, the configurational and the conformationay possibilities become large. The conformational aspects of 1,2,3-trisubstituted cyclohexanes would be complex depending on the nature of substituents because so many parameters are involved.1)