A Conventent Synthesis of Functonalised Heterocuclic Enamines from Alpha-Thioiminium Salts and Active Methylene Compounds Under Solid-Liquid PTC Conditions

Abstract

Functionalised enanines constitute a category of synthetic intermediates useful in carbon, carbon bond formation reactions and have been procured through a variety of condensaticn and extrusion reactions.¹ In one approach active methylene compounds have been condensed with lactin thioethers in the presence of a base at relatively higher temperature.^2,3 In view of our interest in the synthesis of function alised enamines through sulphur extrusion reactions⁴, we have studied the title reaction under non-hydrolytic solid-liquid PTC using solid KF(base)/TEBA(catalyst). A recent report⁵ on the sulphur extrusion of α -thio-iminium salts and their reactions with active methylene compounds prompts us to report our results.