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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 14, 1984 - Issue 7
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Original Articles

Synthesis of 1.3 Dioxans Related with Ambergris

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Pages 661-674 | Published online: 05 Dec 2006
 

Abstract

An improved preparation of the odoriferous acetal (4aR, 6aS, 10aS, 10bR)-4a,7,7,10a-tetramethylper-hydronaphtho[2, 1-d] [1, 3] dioxin (4) and related products are described. The synthesis of 4 is accomplished in six steps, starting with the readily available sesquiterpene (-)-drimenol (5) (overall yield 19.1%).

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