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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 14, 1984 - Issue 9
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Original Articles

A Simple Synthesis of Methyl 7-Oxoheptanoate

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Pages 827-831 | Published online: 19 Dec 2006
 

Abstract

Methyl 7-Oxoheptanoate has recently been used for the synthesis of 2-(6-methoxycarbonylhexyl)-cyclopent-2-en-l-one, a key intermediate for preparation of the pros tanoids! Several methods have been previously adop 3 ted to prepare the title compound: from cycloheptanone, from 1 -methoxycycloheptenef from suberic acid: from methyl 7-iodoheptanoate6,and from 6-bromohexanoic acid or 7 from E-caprolactone.

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