Hydroboration of Unsaturated Amines VIII A Convenient Synthesis of Amino-3 Propanol-1

Abstract

A new route with increased yield and stereoselectivity is reported for the synthesis of amino-3 propanols-1. It involved a hydroboration-oxidation reaction using bora- 9 bicyclo |3, 3, 1| nonane. The amino group was protected by a phosphorylated grouping giving rise to novel and potentially useful phosphorylated reagents.