Synthesis of α, β-Ethylenic Esters in a Heterogenous Solid-Liquid Medium. II - A Transesterification Reaction Linked to a Wittig-Horner Reaction in a Protic Medium

Abstract

The condensation reaction of ethyl or methyl phosphonates with variously functionnalysed aldehydes in the presence of solid potassium carbonate in alcoholic media leads to the direct formation of E α, β unsaturated esters. The alkyl, aryl or heteroaryl substituents of the double bond are provided by the aldehyde and the solvent. The method used involves a solid-liquid transfer process.