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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 16, 1986 - Issue 14
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Original Articles

Improved Syntheses of Vinyl Imidazoles1

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Pages 1761-1770 | Published online: 05 Dec 2006
 

Abstract

A series of vinylimidazoles were synthesized via Wittig reactions on N-tritylimidazole-4-carboxaldehyde. Activated phosphonate ylids afforded yields in excess of 90% while the yields from unactivated ylids ranged from 10–82%. The trityl group may be removed by mild acid hydrolysis in high yield.

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