Stereospecific Synthesis of Endo-6-Aryl-2-Oxobicyclo [3.3.1]Nonanes

Abstract

Two alternate synthetic routes to endo-6-aryl-2-oxobicyclo 3.3.1 nonan [3a-d] by sterespecific catalytic hydrogenetion of the easily accessible 6-arylbicyclo 3.3.1 nona-3,6-dien-2-ones [2a-d], and regioselective oomologation of endo-2-aryl-6-oxobicycle 3.2.1 octanes [4a-d] are described.