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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 17, 1987 - Issue 16
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Original Articles

The Mono-Iodination of 3-Chloro-6-(2-Methoxybenzyl)-Pyridazine

Sarah Jones Organic Chemistry Department, Smith Kline and French Research Ltd., Old Powder Mills, Leigh, Nr. Tonbridge, Kent, TN11 9AN
,
Norman Lewis Organic Chemistry Department, Smith Kline and French Research Ltd., Old Powder Mills, Leigh, Nr. Tonbridge, Kent, TN11 9AN
,
Clare O'farrell Organic Chemistry Department, Smith Kline and French Research Ltd., Old Powder Mills, Leigh, Nr. Tonbridge, Kent, TN11 9AN
&
Philip Wallbank Organic Chemistry Department, Smith Kline and French Research Ltd., Old Powder Mills, Leigh, Nr. Tonbridge, Kent, TN11 9AN
Pages 1907-1917 | Published online: 06 Dec 2006
 
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Abstract

A method of selective mono-iodination, using iodine and ammonium persulphate, is described. In the iodination of the, electron rich, title compound this method was found to be superior to all others attempted.

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