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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 17, 1987 - Issue 4
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Original Articles

Pyrrole Chemistry. Part XXIX A Re-Examination of the Decarboxylation of 4-Acetyl-, 4-Formyl- and 4-Cyanopyrrole-2-Carboxylic Acids

Hugh J. Anderson Department of Chemistry, Memorial University of Newfoundland, St. John's, Newfoundland, Canada, A1B 3X7
,
J. Andrew Clase Department of Chemistry, Memorial University of Newfoundland, St. John's, Newfoundland, Canada, A1B 3X7
&
Charles E. Loader Department of Chemistry, Memorial University of Newfoundland, St. John's, Newfoundland, Canada, A1B 3X7
Pages 401-407 | Published online: 05 Dec 2006
 
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Abstract

Decarboxylation of the readily available 4-acyl-2-pyrrolecarboxylic acids has been neglected owing to the poor yields reported in the literature. This study shows that high yields are possible under the correct reaction conditions.

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