Alternative and Stereoselective Synthesis of 8β(H)-Drimane, A Bicyclic Sesquiterpane of Widespread Occurrence in Petroleums

Abstract

Starting from drimenol, an alternative and stereoselective synthesis of 8β(H)-drimane, a widespread occurring sesquiterpane in petroleums, is described. The epimer 8α(H)-drimane was also prepared and a comparative ¹³C NMR spectral analysis of both stereoisomers was carried out.