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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 17, 1987 - Issue 6
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Original Articles

Stereoselective Synthesis of N-Augenyl Lactams

Charles A. Zezza Department of Chemistry, U-60, Rm 151 215 Glenbrook Rd. University of Connecticut Storrs, Connecticut 06268
&
Michael B. Smith Department of Chemistry, U-60, Rm 151 215 Glenbrook Rd. University of Connecticut Storrs, Connecticut 06268
Pages 729-740 | Published online: 19 Dec 2006
 
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Abstract

The acid catalyzed condensation of lactams and aldehydes is a facile and highly stereoselective preparative route to a wide variety of N-alkenyl lactams of various ring sizes, and it is compatible with a useful range of aldehydes.

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