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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 17, 1987 - Issue 9
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Original Articles

Practical Synthesis of (3R,4R)-4-Acetoxy-3-[1(R)-t-Butyldimethylsilyloxyethyl]Aze-Tidin-2-One. A Key Intermediate for Penem and Carbapenem Synthesis

Masaki Endo Chemical Process Development, Bristol-Myers Pharmaceutical Research and Development Division Candiac, Quebec, Canada, J5R 1J1
Pages 1029-1033 | Published online: 19 Dec 2006
 
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Abstract

The title compound 5 was conveniently synthesized from anhydropenicillin 1 without isolating intermediates in an overall yield of 52%.

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