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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 18, 1988 - Issue 3
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Original Articles

Simple Synthesis of 1-(Azacycloalkyl)Indoles Using Exclusive Ortho α-Chloroacetylation of N-(Azacycloalkyl)Anilines

Kazuyuki Sasakura Shionogi Research Laboratories, Shionogi & Co., Ltd., Fukushima-ku, Osaka, 553, Japan
,
Makoto Adachi Shionogi Research Laboratories, Shionogi & Co., Ltd., Fukushima-ku, Osaka, 553, Japan
&
Tsutomu Sugasawa Shionogi Research Laboratories, Shionogi & Co., Ltd., Fukushima-ku, Osaka, 553, Japan
Pages 265-273 | Published online: 05 Dec 2006
 
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Abstract

Use of 2-(azacycloalkyl)amino-α-chloroacetophenones (4) as starting material makes possible simple synthesis of 1-(azacycloalkyl)-indoles (2).

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