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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 18, 1988 - Issue 8
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Original Articles

A Facile O-Alkyl Cleavage of Esters with Sodium Hydrogen Selenide

Fangming Kong Department of Chemistry, Hangzhou University, Hangzhou, China
,
Jian Chen Department of Chemistry, Hangzhou University, Hangzhou, China
&
Xunjun Zhou Department of Chemistry, Hangzhou University, Hangzhou, China
Pages 801-804 | Published online: 05 Dec 2006
 
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Abstract

Sodium hydrogen selenide generated in the dipolar aprotic solvent DMF is shown to be an effectively selective reagent for the dealkylation of esters to give the corresponding carboxylic acids in good yields.

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